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Professor Jason S. Lewis to receive the 2020 Bioconjugate Chemistry Lectureship Award

Bioconjugate Chemistry and the ACS Division of Polymeric Materials Science and Engineering (PMSE) are pleased to announce the recipient of this year’s 2020 Bioconjugate Chemistry Lectureship Award.  Please join us in congratulating Professor Jason S. Lewis, Ph.D., of the Memorial Sloan Kettering Cancer Center (MSK) in New York. 

Jason S. Lewis is currently the Emily Tow Jackson Chair in Oncology at Memorial Sloan Kettering Cancer Center (MSK) in New York. He is the Chief Attending of the Radiochemistry & Imaging Sciences Service and serves as the Vice Chair of Research in the Department of Radiology at MSK. He holds a joint appointment in the Molecular Pharmacology Program, and he is the Director of the Radiochemistry & Molecular Imaging Probe Core in the Sloan-Kettering Institute. He also holds appointments as a Professor at the Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, New York, NY and the Weill Cornell Medical College, Cornell University, New York, NY. He is an Adjunct Professor in the Department of Biomedical Imaging and Image Guided Therapy, The Medical University of Vienna, Vienna, Austria. 

Lewis earned a B.Sc. in Chemistry (1992) and a M.Sc. (1993) in Chemistry from the University of Essex and then in 1996 obtained a Ph.D. in Biochemistry from the University of Kent with Professor Philip J. Blower. His postdoctoral work was with Professors Carolyn J. Anderson and Michael J. Welch at the Washington University School of Medicine (WUSM).  Subsequently he joined the WUSM faculty as an Assistant Professor of Radiology at the Mallinckrodt Institute of Radiology (2003-2008). Professor Lewis then joined MSK in 2008. 

Professor Lewis’ research program is a molecular imaging-based program focused on radiopharmaceutical development as well as the study of multimodality (PET, CT & MRI) small- and biomolecule-based agents and their clinical translation. He has worked on the development of small molecules targeting aberrant metabolism, as well as radiolabeled peptides and antibodies probing the overexpression of receptors and antigens on tumors. His research interests are focused on the development of new molecular imaging agents for the diagnosis and treatment of cancer. He has published >300 papers and reviews in the field of radiochemistry and molecular imaging.

The Bioconjugate Chemistry Lectureship Award is presented annually to recognize outstanding researchers for important recent advances in interfacing synthetic and biological systems. Jason S. Lewis joins a prestigious class of past recipients, including Heather D. MaynardWolfgang J. ParakMatthew B. Francis and Xiaoyuan Chen. “Jason Lewis is a highly innovative, driving force in the rapidly evolving and critical field of radiopharmaceuticals” says Vincent Rotello, Ph.D., Editor-in-Chief of Bioconjugate Chemistry.

Read a selection of papers from Professor Lewis:

A Systematic Evaluation of Antibody Modification and 89Zr-Radiolabeling for Optimized Immuno-PET

Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall

Bioorthogonal Masking of Circulating Antibody–TCO Groups Using Tetrazine-Functionalized Dextran Polymers

Click Chemistry and Radiochemistry: The First 10 Years

PET Imaging of Extracellular pH in Tumors with 64Cu- and 18F-Labeled pHLIP Peptides: A Structure–Activity Optimization Study